发明名称 |
Novel bio-sensor for the detection of small molecules |
摘要 |
This present invention provides methods for the detection of small molecules in samples comprising the steps a) coupling a nanoparticle (NP) or microparticle (MP) to an aptamer specific for the small molecule to be detected to form a NP-aptamer conjugate b) contacting the NP-aptamer conjugate with the sample; and c) detecting a change in the size, surface potential, or mobility of the NP-aptamer conjugate, wherein the change is indicative of the presence of the small molecule. The present invention also provides for and a biosensor comprising nanoparticles coupled to aptamers to provide nanoparticle aptamer-conjugates (NP-aptamer). |
申请公布号 |
AU2014215764(A1) |
申请公布日期 |
2015.09.17 |
申请号 |
AU20140215764 |
申请日期 |
2014.02.05 |
申请人 |
VICTORIA LINK LIMITED |
发明人 |
ALSAGER, OMAR AHMED H.;HODGKISS, JUSTIN MARK;KUMAR, SHALEN;MCNATTY, KENNETH PATTRICK |
分类号 |
C12Q1/68;C12N15/115;G01N33/53 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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