MELANIN MODIFICATION COMPOSITIONS AND METHODS OF USE

摘要

A method for the modification of melanin distribution, and the composition thereof to modify melanin distribution are disclosed. A method for the reduction of melanin distribution, and the composition thereof to reduce melanin distribution are disclosed. A representative composition comprises 4-ethoxybenzaldehyde and one or more additional active agents as well as a pharmaceutically acceptable carrier or excipient. Carriers and excipients may be formulated for topical administration. Compositions may also be formulated for transdermal administration. The compositions may be used for the prevention and treatment of pigmentation disorders, by way of non-limited example, post-inflammatory hyperpigmentation and others. The compositions may be used for lightening skin.

主权项

1. A composition comprising from about 0.01% to about 2% substituted benzaldehyde, wherein the substituted benzaldehyde is 2-ethoxybenzaldehyde, 4-ethoxybenzaldehyde, 4-allyloxybenzaldehyde or 4-propoxybenzaldehyde, from about 0.01% to about 5.0% each of Retinol, Niacinamide, Tetrahexyldecyl Ascorbate, Glycyrrhiza Glabra (Licorice) Root Extract, Hexyl Resorcinol, ethyl linoleate, and a pharmaceutically or cosmetically acceptable carrier.