摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide an apparatus and a method for growing a crystal of a protein, capable of growing (forming) a high-quality protein crystal large enough for use in a neutron diffraction method, with excellent reproducibility. <P>SOLUTION: The apparatus 1 for growing a crystal of a protein includes a controller 2 and a chamber 3 sealed with an inert gas and connected to the controller 2. The controller 2 includes: a means of reducing the pressure of the chamber 3 in which a seed crystal 16 of the protein placed in a mixed aqueous solution 15 comprising a raw solution of the protein and a crystallizing agent mixed together is put; a means of stopping reducing the pressure of the chamber 3 when the crystal of the protein begins to grow; and a means of injecting the raw solution of the protein into the mixed aqueous solution 15 when the surface of the crystal of the protein begins to dissolve. <P>COPYRIGHT: (C)2012,JPO&INPIT</p> |