Disclosed herein are markers associated with sensitivity to treatment with proteasome inhibitors. Sensitivity is observed when RAS gene is wild type in tumor cells. Compositions and methods are provided to assess markers of marker genes to predict outcome with proteasome inhibition treatment
申请公布号
EP2776586(A4)
申请公布日期
2015.09.16
申请号
EP20120846898
申请日期
2012.11.09
申请人
MILLENNIUM PHARMACEUTICALS, INC.
发明人
BERGER, ALLISON;BERNARD, HUGHES;CHATTOPADHYAY, NIBEDITA;KOENIG, ERIK, M.;MULLIGAN, GEORGE, J.;SCHU, MATTHEW, C.