METHOD FOR MANUFACTURING USEFUL SUBSTANCE IN WHICH HIGH-DENSITY CULTURED STRAIN OF FILAMENTOUS FUNGI IS USED

摘要

An object to be achieved by the present invention is to culture a filamentous fungus at a high density, thereby enabling mass production of a useful substance. The present invention provides a method of producing a substance, including the steps of: culturing a mutant filamentous fungus with no expression of ±-1,3-glucan to allow the filamentous fungus to produce a substance; and collecting the resulting substance.