发明名称 PROCESS FOR MAKING THE 17-TRIFLATE INTERMEDIATE OF ABIRATERONE-3-ACETATE
摘要 <p>The present invention relates to a process for making the compound 3β-acetoxy- androsta-5,16-dien-17-yl trifluoromethanesulfonate of formula (5) and is characterized in that dehydroepiandrosterone-3-acetate of formula (2) is reacted with a triflating agent, preferably trifluoromethanesulfonic anhydride, in an inert solvent in the absence of an organic base.</p>
申请公布号 EP2917226(A1) 申请公布日期 2015.09.16
申请号 EP20120790830 申请日期 2012.11.09
申请人 SYNTHON BV 发明人 DYMACEK, BOHUMIL;CASTULIK, JAKUB
分类号 C07J43/00;C07J75/00 主分类号 C07J43/00
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