发明名称 |
[4-(5-AMINOMETHYL-2-FLUORO-PHENYL)-PIPERIDIN-1-YL]-[7-FLUORO-1-(2-METHOXY-ETHYL)-4TRIFLUOROMETHOXY-1H-INDOL-3-YL]METHANONE AS AN INHIBITOR OF MAST CELL TRYPTASE |
摘要 |
<p>The present invention is directed to an indole benzylamine compound of formula I: useful as an inhibitor of tryptase. In addition, the present invention is directed to the use of the compound for treating a patient suffering from, or subject to, a physiological condition in need of amelioration by inhibition of tryptase, comprising administering to the patient of a therapeutically effective amount of the compound, and to a pharmaceutical composition comprising a pharmaceutically effective amount of the compound of formula I, and a pharmaceutically acceptable carrier.</p> |
申请公布号 |
EP2367812(B1) |
申请公布日期 |
2015.09.16 |
申请号 |
EP20090791693 |
申请日期 |
2009.08.20 |
申请人 |
SANOFI |
发明人 |
CHOI-SLEDESKI, YONG, MI;CHOY, NAKYEN;POLI, GREGORY, BERNARD;SHAY, JOHN, J., JR.;SHUM, PATRICK, WAI-KWOK;SLEDESKI, ADAM, W. |
分类号 |
C07D401/06;A61K31/404;A61P29/00 |
主分类号 |
C07D401/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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