发明名称 NOVEL SUBSTITUTED PYRIDO-PIPERAZINONE DERIVATIVES AS GAMMA SECRETASE MODULATORS
摘要 <p>The present invention is concerned with novel substituted pyrido-piperazinone derivatives of Formula (I) wherein R1, R2, R3, R4, R5, L, Z and X have the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.</p>
申请公布号 KR20150105319(A) 申请公布日期 2015.09.16
申请号 KR20157017828 申请日期 2014.01.16
申请人 JANSSEN PHARMACEUTICA N. V 发明人 BISCHOFF FRANCOIS PAUL;VELTER ADRIANA INGRID;ROMBOUTS FREDERIK JAN RITA;DE CLEYN MICHEL ANNA JOZEF;VAN BRANDT SVEN FRANCISCUS ANNA;GIJSEN HENRICUS JACOBUS MARIA;ZAVATTARO CHIARA;VAN DEN KEYBUS FRANS ALFONS MARIA
分类号 C07D471/04;A61K31/343;A61K31/4164;A61K31/4196;A61K31/4985;C07D405/14 主分类号 C07D471/04
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