发明名称 |
A COMPOSITION FOR TREATING DIABETES OR DIABESITY COMPRISING OXYNTOMODULIN ANALOG |
摘要 |
Disclosed are a composition for preventing or treating diabetes, diabesity or diabetic complications, containing an oxyntomodulin analog as an active ingredient and a method for treating diabetes, diabesity or diabetic complications, including administering a pharmaceutically effective amount of an oxyntomodulin analog to a subject. The oxyntomodulin analog shows a greater activity to activate a GLP-1 receptor and a glucagon receptor, than native oxyntomodulin. The oxyntomodulin analog induces an expansion of beta-cells and increases insulin secretion, thereby reducing blood glucose levels that were increased due to a high-calorie and high-fat diet. The oxyntomodulin analog induces decreases in a body weight and appetite to improve insulin sensitivity and is useful in maintaining normal blood glucose levels. |
申请公布号 |
EP2916860(A1) |
申请公布日期 |
2015.09.16 |
申请号 |
EP20130853226 |
申请日期 |
2013.11.06 |
申请人 |
HANMI PHARM. CO., LTD. |
发明人 |
KIM, JIN SUN;KIM, DAE JIN;LEE, SANG HYUN;JUNG, SUNG YOUB;KWON, SE CHANG |
分类号 |
A61K38/26;A61K39/395;A61P3/10;C07K14/605 |
主分类号 |
A61K38/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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