Activated leukocyte composition and uses for wound healing

摘要

Disclosed are therapeutic, blood-derived activated leukocyte compositions, methods of making them, and methods of using the compositions to repair or promote the prevention and healing of wounds.

主权项

1. A method for treating a wound comprising administering to the wound the composition comprising activated leukocytes, wherein the activated leukocytes are made by a method comprising:
a) incubating human leukocytes for a period of time so that the leukocytes transition from a quiescent to a functionally active state; b) subjecting the leukocytes to hypo-osmotic shock; and c) adding to the leukocytes of step b) a salt solution in an amount which restores isotonicity.