发明名称 |
Inhibitors of HCV NS5A |
摘要 |
The present invention provides compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection. |
申请公布号 |
US9133170(B2) |
申请公布日期 |
2015.09.15 |
申请号 |
US201214364818 |
申请日期 |
2012.12.13 |
申请人 |
HOFFMANN-LA ROCHE INC. |
发明人 |
Brinkman John A.;Sarabu Ramakanth;So Sung-Sau |
分类号 |
C07D233/64;C07D237/26;C07D403/14;C07D487/06;A61K31/55;C07D487/04;A61K31/551;A61K31/4178;A61K45/06;A61K38/21 |
主分类号 |
C07D233/64 |
代理机构 |
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代理人 |
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主权项 |
1. A compound of Formulae I-III wherein: each A is independently selected from the group consisting of each R1 and R2 are independently selected from the group consisting of H, lower alkyl, or aryl; each R3 is independently selected from the group consisting of H, lower alkyl, or C(═O)OR4;
R4 is lower alkyl; each X is independently selected from the group consisting of H and Cl; and each Y1 and Y2 are independently selected from the group consisting of H or F; or a pharmaceutically acceptable salt thereof. |
地址 |
Nutley NJ US |