发明名称 Inhibitors of HCV NS5A
摘要 The present invention provides compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
申请公布号 US9133170(B2) 申请公布日期 2015.09.15
申请号 US201214364818 申请日期 2012.12.13
申请人 HOFFMANN-LA ROCHE INC. 发明人 Brinkman John A.;Sarabu Ramakanth;So Sung-Sau
分类号 C07D233/64;C07D237/26;C07D403/14;C07D487/06;A61K31/55;C07D487/04;A61K31/551;A61K31/4178;A61K45/06;A61K38/21 主分类号 C07D233/64
代理机构 代理人
主权项 1. A compound of Formulae I-III wherein: each A is independently selected from the group consisting of each R1 and R2 are independently selected from the group consisting of H, lower alkyl, or aryl; each R3 is independently selected from the group consisting of H, lower alkyl, or C(═O)OR4; R4 is lower alkyl; each X is independently selected from the group consisting of H and Cl; and each Y1 and Y2 are independently selected from the group consisting of H or F; or a pharmaceutically acceptable salt thereof.
地址 Nutley NJ US