| 摘要 |
The present disclosure generally provides a multiple balloon assembly used as part of the distal region of a medical device that is capable of delivering a therapeutic agent into a body vessel having bodily fluid. The multiple balloon assembly comprises an inner balloon and an outer balloon. The outer balloon further comprises a proximal taper region, a middle region, and a distal taper region. The inflation of the inner balloon causes the middle region of the outer balloon to contact the inner wall of the body vessel, thereby, occluding the flow of fluid through the body vessel. The proximal taper region and the distal taper region are configured such that they do not touch the inner wall of the body vessel. One of the distal taper and proximal taper regions has a plurality of apertures configured to allow for the therapeutic agent to be delivered into the body vessel at a predetermined rate. A medical device that incorporates the multiple balloon assembly of the present disclosure, as well as a method for using the medical device and multiple balloon assembly are further disclosed. |
| 主权项 |
1. A multiple balloon assembly located in the distal region of a medical device having a catheter that defines an inflation lumen, a therapeutic agent delivery lumen, and a wire guide lumen, the multiple balloon assembly capable of delivering a therapeutic agent into a body vessel, the body vessel having bodily fluid and an inner wall, the multiple-balloon assembly comprising:
an inner balloon having a first end and a second end, the first end being in contact with both the wire guide lumen and the inflation lumen, the second end being in contact with only the wire guide lumen, the inner balloon being in communication with the inflation lumen and adapted to move between a collapsed state and an expanded state; and an outer balloon having a first end and a second end, the outer balloon being disposed around the inner balloon, the outer balloon being in communication with the therapeutic agent delivery lumen and defining a proximal taper region, a middle region, and a distal taper region; the proximal taper region including the first end of the outer balloon being in contact with the catheter; the middle region being in contact with the inner balloon when the inner balloon is in the expanded state; the distal taper region including the second end of the outer balloon being in contact with the wire guide lumen; only the proximal taper region of the outer balloon having a plurality of apertures adapted to allow for the therapeutic agent to be delivered into the body vessel, wherein in the expanded state the plurality of apertures are out of communication with the inner wall of the body vessel; wherein the movement of the inner balloon to the expanded state forces the middle region of the outer balloon to contact the wall of the body vessel and to occlude the flow of fluid through the vessel. |
