Cardiopulmonary bypass circuit including a filtration device

摘要

Apparatus and methods for extracorporeal blood filtration involving the connection of a patient's cardiovascular circulation to an extracorporeal circulatory circuit, and filtration devices suitable for use in such apparatus and methods are disclosed. Such filtration devices include a filter medium comprising a layer of non-woven fabric (21) impregnated with porous beads (22) and carrying a porous screen (23) on at least one side. This invention enables the removal or particular molecular species such as pro-inflammatory cytokines from a patient's circulation, and is of particular utility in cardiopulmonary bypass and haemodialysis-like procedures.

主权项

1. A cardiopulmonary bypass circuit including a filtration device comprising a housing having inlet and outlet ports connected in fluid communication with the cardiopulmonary bypass circuit and a filter medium disposed in a blood flow path of the cardiopulmonary bypass circuit between said inlet and outlet ports, wherein the filter medium comprises a single layer of non-woven fabric having a weight of up to 500 g/m2 and porous beads anchored to fibres of the non-woven fabric by means of adhesive and the filtration device further comprises a porous screen having pores of between 20 μm and 100 μm in diameter on at least a downstream side of the filter medium, wherein the porous beads have a greater diameter than the pores of the porous screen.