Pharmaceutical compositions of linezolid

摘要

The present invention relates to stable pharmaceutical compositions comprising linezolid crystalline Form III with one or more pharmaceutically acceptable excipients, wherein the composition retains linezolid in its original crystalline form.

主权项

1. A process for preparing a stable pharmaceutical composition comprising linezolid Form III and at least one pharmaceutically acceptable excipient, comprising
wet granulating the linezolid Form III and the pharmaceutically acceptable excipient using 10% w/w of water based on total weight of the core tablet as a granulation solvent, wherein the stable pharmaceutical composition retains more than 80% crystallinity of linezolid form III.