| 主权项 |
1. A compound of formula (I) wherein A is C1-6 alkylene, C2-6 alkenylene, C2-6 alkynylene or C1-6 heteroalkylene; Q is CR4; X is CR7 or N; Y is CH; n is 1, 2 or 3; m is 1, 2 or 3; R1 is H, F, Cl, Br, I, OH, NH2, an alkyl group or a heteroalkyl group; R2 is H, F or Cl; R3 is an ethyl, a 2-propyl, a C3-C6cycloalkyl, a phenyl or a pyridyl group; all of which may be substituted with one, two, three or more fluorine atoms or amino groups; R4 is hydroxyl or a group of formula OSO3H, OPO3H2, OCH2OPO3H2, or OCOCH2CH2COOH; R5 is selected from the following groups: R6 is H, F, Cl or OMe; R7 is H, F, Cl or a methoxy group which may be substituted by one, two or three fluorine atoms; or R7 and R3 together form a bridge of the formula —O—CH2—N(Me)- or —O—CH2—CH(Me)-; and R8 is a C1-6 heteroalkyl group; or a pharmacologically acceptable salt, solvate, hydrate or formulation thereof. |
