| 发明名称 | Radiolabelled rotenone derivatives and their use in SPECT imaging | ||
| 摘要 | The present application discloses a compound of formula (I) or (II):;wherein X is gamma-emitting radionuclide. Also disclosed is a pharmaceutical composition comprising the compound of formula (I), the compound of formula (II), or a mixture thereof, and a physiologically acceptable vehicle and a method of imaging a region in a patient, which includes administering to the patient a diagnostically effective amount of the pharmaceutical composition comprising the compound of formula (I), the compound of formula (II), or a mixture thereof. | ||
| 申请公布号 | US9133208(B2) | 申请公布日期 | 2015.09.15 |
| 申请号 | US201213549093 | 申请日期 | 2012.07.13 |
| 申请人 | NORDION (CANADA) INC. | 发明人 | Wei Lihui;Yan Xuxu;Bensimon Corinne;Ruddy Terrence David |
| 分类号 | A61K51/00;A61M36/14;C07D493/14 | 主分类号 | A61K51/00 |
| 代理机构 | Arent Fox LLP | 代理人 | Arent Fox LLP |
| 主权项 | 1. A compound of formula (I) or (II): wherein X is a gamma-emitting radionuclide selected from the group consisting of 123I, 124I, 125I and 131I. | ||
| 地址 | Ontario CA | ||