主权项 |
1. A compound of the formula (I)in which
the ring Q is a group of the formulawhere
* is the attachment site to —CH2-R2, ** is the attachment site to the triazine ring, R1a is hydrogen or methyl, R1b is hydrogen or fluorine, R1c is hydrogen or chlorine, A1 is N or CH, A3 is N, CH or C—F, R2 is 3,3,3-trifluoroprop-1-yl, 2,2,3,3-tetrafluoroprop-1-yl, 2,2,3,3,3-pentafluoroprop-1-yl, phenyl or pyridyl,
where phenyl is substituted by 1 to 3 fluorine substituents,andwhere pyridyl may be substituted by 1 fluorine substituent, R3 is difluoromethyl, trifluoromethyl, (C1-C6)-alkyl, cyclopropyl, cyclobutyl, cyclopentyl, methylsulphonylamino, methoxycarbonylamino, phenyl, pyrazolyl, oxazolyl or pyridyl,
where (C1-C6)-alkyl may be substituted by 1 to 3 substituents independently of one another selected from the group consisting of fluorine, trifluoromethyl, cyclopropyl, cyclobutyl, cyclopentyl, difluoromethoxy, trifluoromethoxy, methoxy and ethoxy,andwhere phenyl, pyrazolyl, oxazolyl and pyridyl may be substituted by 1 or 2 substituents independently of one another selected from the group consisting of fluorine, chlorine, difluoromethyl, trifluoramethyl, methyl, ethyl, cyclopropyl, cyclobutyl, cyclopentyl, trifluoromethoxy, methoxy and ethoxy, R4 is hydroxy or amino, or a salt thereof. |