| 发明名称 |
Use of LNA ApoB antisense oligomers for the treatment of acute coronary syndromes |
| 摘要 |
The present invention relates to the use of LNA antisense apoB oligonucleotides for the treatment of acute coronary syndrome. |
| 申请公布号 |
US9132147(B2) |
申请公布日期 |
2015.09.15 |
| 申请号 |
US200913142929 |
申请日期 |
2009.12.18 |
| 申请人 |
|
发明人 |
Bagger Yu;Straarup Ellen Marie |
| 分类号 |
A61K48/00;C07H21/02;C07H21/04;A61K31/712;A61K31/713;C12N15/113 |
主分类号 |
A61K48/00 |
| 代理机构 |
Fish & Richardson P.C. |
代理人 |
Fish & Richardson P.C. |
| 主权项 |
1. A method of treatment of acute coronary syndrome, comprising administering to a patient an oligonucleotide comprising GsTstsgsascsascstsgsTsmC (SEQ ID NO:41), wherein upper case letters indicate LNA, mC indicates methyl C-LNA, and the s represents phosphorothioate linkage to a patient suffering from acute coronary syndrome. |
| 地址 |
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