Topical antimicrobial compositions

摘要

Disclosed are topical antimicrobial compositions. The compositions are useful for disinfecting and treating microbial infections of the skin or mucosa of humans and animals. The antimicrobial compositions include a salt of amino acid anion and quaternary ammonium cation, comprising the general formula:;

主权项

1. A method for disinfecting body surface, said method comprising administrating to body surface with a biocidal effective amount of a composition comprising:
(a) a quaternary ammonium amino acid carboxylate salt selected from the group consisting of quaternary ammonium oxopyrrolidine-2-carboxylate, having the formula  and quaternary ammonium N-acetylated alanine carboxylate, having the formula  wherein R1, R2, R3, R4 independently are a C8-C14 alkyl group; and (b) a solvent selected from the group consisting of water, propylene glycol, polyethylene glycol, ethanol and a combination thereof.