SUBSTITUTED (3E)-3-METHYL-N-(5-PHENYL-1,3,4-THIADIAZOL-2-YL)-4-(PYRIDIN-2-YL)BUT-3-ENAMIDE AS FACTOR IXA INHIBITORS

摘要

The present invention deals with substituted 3-(pyridin-2-ylimino) butanamide compounds as factor IXa inhibitors that can be useful for treating and preventing thrombosis and thrombosis-related disorders, such as unstable angina, acute myocardial infarction, myocardial ischemia reperfusion injury, venous thrombosis, sepsis, glomerulonephritis and cerebrovascular disorder.