发明名称 NOVEL 6-FUSED HETEROARYLDIHYDROPYRIMIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION
摘要 The invention provides novel compounds having the general formula (I): wherein R1, R2, R3, R4, R5, R6, X, Y, W and n are as described herein, compositions including the compounds and methods of using the compounds. These compounds useful for therapy and/or prophylaxis in a human, and in particular to Hepatitis B virus (HBV) inhibitors by targeting on HBV capsid for the treatment of HBV infection.
申请公布号 WO2015132276(A1) 申请公布日期 2015.09.11
申请号 WO2015EP54454 申请日期 2015.03.04
申请人 F. HOFFMANN-LA ROCHE AG;HOFFMANN-LA ROCHE INC. 发明人 GUO, LEI;HU, TAISHAN;KOU, BUYU;LIN, XIANFENG;SHEN, HONG;SHI, HOUGUANG;YAN, SHIXIANG;ZHANG, WEIXING;ZHANG, ZHISEN;ZHOU, MINGWEI;ZHU, WEI
分类号 C07D487/04;A61K31/4985;A61P31/12;C07D498/04;C07D513/04 主分类号 C07D487/04
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