发明名称 |
NOVEL 6-FUSED HETEROARYLDIHYDROPYRIMIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION |
摘要 |
The invention provides novel compounds having the general formula (I): wherein R1, R2, R3, R4, R5, R6, X, Y, W and n are as described herein, compositions including the compounds and methods of using the compounds. These compounds useful for therapy and/or prophylaxis in a human, and in particular to Hepatitis B virus (HBV) inhibitors by targeting on HBV capsid for the treatment of HBV infection. |
申请公布号 |
WO2015132276(A1) |
申请公布日期 |
2015.09.11 |
申请号 |
WO2015EP54454 |
申请日期 |
2015.03.04 |
申请人 |
F. HOFFMANN-LA ROCHE AG;HOFFMANN-LA ROCHE INC. |
发明人 |
GUO, LEI;HU, TAISHAN;KOU, BUYU;LIN, XIANFENG;SHEN, HONG;SHI, HOUGUANG;YAN, SHIXIANG;ZHANG, WEIXING;ZHANG, ZHISEN;ZHOU, MINGWEI;ZHU, WEI |
分类号 |
C07D487/04;A61K31/4985;A61P31/12;C07D498/04;C07D513/04 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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