发明名称 ACCELERATION SENSITIVE INDICATOR
摘要 An acceleration sensitive indicator (1, 1', 1", 31, 31', 51, 61, 71, 81, 121, 121', 131) for indicating a centrifugation status of a biological sample, a sample container (100, 100') comprising the acceleration sensitive indicator, a centrifuge (200) for centrifuging sample containers (100, 100') and an analytical system (300) for analyzing centrifuged samples are disclosed. The indicator (1, 1', 1", 31, 31', 51, 61, 71, 81, 121, 121', 131) comprises at least one closed chamber (2, 2', 32, 32', 112) formed between two opposite surfaces. The chamber (2, 2', 32, 32', 112) comprises at least one indication zone (3, 3', 3", 33, 53, 63, 73, 93, 123, 124, 124', 133, 134), the at least one indication zone (3, 3', 3", 33, 53, 63, 73, 93, 123, 124, 124', 133, 134) comprising at least two fluid transfer zones (4, 4', 5, 5', 16, 17, 18) or at least one particle transfer zone (34, 54, 74, 75, 76, 77, 82, 122, 125, 125', 135). The at least one fluid transfer zone (4, 4', 5, 5', 16, 17, 18) comprises at least one solid carrier phase (14) and at least one fluid (15, 15') stabilized in the solid carrier phase (14), or at least one non-stabilized non-Newtonian fluid (13) having thixotropic and/or shear thinning properties. The at least one particle transfer zone (34, 54, 74, 75, 76, 77, 82, 122, 125, 125', 135) comprises at least one particle stabilizing fluid (35, 83) comprising stabilized dispersed particles (36, 84, 85, 86, 87). In particular, the at least one fluid (13, 15, 15') or particles (36, 84, 85, 86, 87) have a distribution with respect to the at least one indication zone (3, 3', 3", 33, 53, 63, 73, 93, 123, 124, 124', 133, 134), which is changeable only upon application of a g-force above a threshold value, the change of distribution indicating the centrifugation status.
申请公布号 HK1201918(A1) 申请公布日期 2015.09.11
申请号 HK20150102349 申请日期 2015.03.09
申请人 F. HOFFMANN LA ROCHE AG 发明人 GEZA BURGHARDT G;MICHAEL GLAUSER M;OLIVER GUTMANN O;DANIEL MUELLER D;EDWIN OOSTERBROEK E;ROGER SANDOZ R;EMAD SAROFIM E;GORAN SAVATIC G
分类号 G01N 主分类号 G01N
代理机构 代理人
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