CARDIAC NEURAL CREST CELLS AND METHODS OF USE THEREOF

摘要

Cardiac neural crest cells and methods for making and using are described. Specifically, the disclosure provides methods of producing cardiac neural crest cells comprising culturing a plurality of stem cells with noggin and leukemia inhibitory factor, and methods of treating a cardiac injury in a subject in need thereof comprising administering a therapeutically effective amount of a pharmaceutical composition comprising cardiac neural crest cells.