发明名称 |
CHIMERIC ANTIGEN RECEPTOR |
摘要 |
Provision of a chimeric antigen receptor (CAR) comprising a disialoganglioside (GD2)-binding domain which comprises a) a heavy chain variable region (VH) having complementarity determining regions (CDRs) with the following sequences: b) a light chain variable region (VL) having CDRs with the following sequences: T cells expressing such a CAR are useful in the treatment of some cancers. |
申请公布号 |
CA2941159(A1) |
申请公布日期 |
2015.09.11 |
申请号 |
CA20152941159 |
申请日期 |
2015.03.06 |
申请人 |
UCL BUSINESS PLC |
发明人 |
PULE, MARTIN;ANDERSON, JOHN;THOMAS, SIMON |
分类号 |
C07K19/00;A61K39/395;A61P35/00;C07K14/00;C07K14/705;C07K14/725;C07K16/30;C12N15/13 |
主分类号 |
C07K19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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