摘要 |
<p>The present invention offers a greener and efficient methodology for the synthesis of 2-propenoic acid-3-phenyl-alkyl ester (cinnamate ester) compounds in the supercritical carbon dioxide as a solvent. This methodology has several advantages like greener bio-catalyst and greener supercritical carbon dioxide as a reaction media which fulfilled a complete greener aspect. Moreover, the present invention reports an efficient method for the synthesis of various types of cinnamate esters with broad substrate array (alkyl, cycloalkyl, aryl and heterocyclic alkyl). The reaction method used is simple and suitable for the large-scale industrial application, which involves the simple work-up process to get desired product. This methodology offers 30-98 % yield of the corresponding 2-propenoic acid-3-phenyl-alkyl ester (cinnamate ester) compounds.</p> |