PROCESS FOR THE PREPARATION OF LAMIVUDINE

摘要

The present invention relates to an improved process for preparing pure Lamivudine of Formula I, which comprises treating Lamivudine (I) with hydrochloric acid to give Lamivudine hydrochloride salt (VIII); optionally isolating Lamivudine hydrochloride salt (VIII), desalifying the Lamivudine hydrochloride salt (VIII) to give Lamivudine; and isolating pure Lamivudine (I).