METHOD OF MITIGATING THE SIDE EFFECTS OF A PHOSPHODIESTERASE TYPE V INHIBITOR IN A SUBJECT

摘要

The invention relates to a method of mitigating the side effects of a phosphodiesterase type V (PDE5) inhibitor in a subject that experiences side effects when administered a PDE5 inhibitor. The method comprises simultaneously administering to the subject active ingredients comprising an effective amount of a tramadol material and an effective amount of a PDE5 inhibitor. The invention also relates to a method of administering a PDE5 inhibitor to a subject who is otherwise unable or unwilling to be administered the PDE5 inhibitor due to intolerable side effects.