发明名称 |
METHODS AND SYSTEMS USING NON-LABELED ANTIMETABOLITES AND ANALOGS THEREOF AS THERANOSTIC AGENTS |
摘要 |
A method, computer-readable medium and system of planning, guiding and/or monitoring a therapeutic procedure, can include: receiving a non-labeled therapeutic agent by a subject, said non-labeled therapeutic agent comprises at least one type of water-exchangeable proton that is exchangeable with protons in surrounding water molecules so as to enhance detection by a chemical exchange saturation transfer (CEST) process; acquiring a plurality of CEST magnetic resonance images of said non-labeled therapeutic agent within a region of interest of said subject for a corresponding plurality of times; and assessing at least one of a therapeutic plan or therapeutic effect of said non-labeled therapeutic agent in tissue of said subject based on said plurality of magnetic resonance images |
申请公布号 |
WO2015134934(A1) |
申请公布日期 |
2015.09.11 |
申请号 |
WO2015US19291 |
申请日期 |
2015.03.06 |
申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
LIU, GUANSHU;LI, YUGUO;VAN ZIJL, PETER C.M.;ZHOU, SHINBIN;VOGELSTEIN, BERT |
分类号 |
A61B5/055;G01R33/20;G01R33/48 |
主分类号 |
A61B5/055 |
代理机构 |
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代理人 |
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地址 |
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