发明名称 BETA-HAIRPIN PEPTIDES HAVING ANTI-VIRAL PROPERTIES AGAINST THE DENGUE VIRUS
摘要 The invention relates to structurally constrained synthetic peptides that have been optimised to form a beta-hairpin structure. The peptides can inhibit or reduce the infection caused by the dengue virus (DENV). The invention also relates to pharmaceutical compositions containing these synthetic peptides, said pharmaceutical compositions being suitable for preventing and/or treating the infections caused by DENV. Furthermore, the invention provides a method for treating the infections caused by this virus.
申请公布号 WO2015131858(A2) 申请公布日期 2015.09.11
申请号 WO2015CU00002 申请日期 2015.02.26
申请人 CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA 发明人 CHINEA SANTIAGO, GLAY;HUERTA GALINDO, VIVIAN;MARTÍN DUNN, ALEJANDRO, MIGUEL;GARAY PÉREZ, HILDA, ELISA;REYES ACOSTA, OSVALDO;FALCÓN CAMA, VIVIANA;PUPO GÓMEZ, DIANNE;YERO DÍAZ, ALEXIS;MÁRQUEZ PERERA, GABRIEL, JESÚS;SARRÍA NÚÑEZ, MÓNICA;GUIROLA CRUZ, OSMANY;GARATEIX SUÁREZ, ROCIO;ALVAREZ PÉREZ, KAREN;GONZÁLEZ BLANCO, SONIA;VÁZQUEZ CASTILLO, MARIELA;GONZÁLEZ LÓPEZ, LUIS, JAVIER
分类号 A61K38/00 主分类号 A61K38/00
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