摘要 |
A method for preventing, treating and/or reversing a disease, condition or state in a subject in need thereof by administering to the subject an effective amount of the (-)-perhexiline or a pharmaceutically acceptable salt, prodrug or derivative thereof, substantially free of (+)- perhexiline, or a pharmaceutical composition containing same. The diseases, components, features, conditions or states are associated with, caused by, manifesting, or resulting in, a reduced cellular redox state, hypoxia, an undesired lactic acid production or lactate utilization, and/or lactic acidosis. |
申请人 |
ADELAIDE RESEARCH & INNOVATION PTY LTD;HEART METABOLICS LIMITED;CENTRAL ADELAIDE LOCAL HEALTH NETWORK INC.;DRUZGALA, PASCAL-JEAN;MILNER, PETER;SALLUSTIO, BENEDETTA;LICARI, JOHN |
发明人 |
DRUZGALA, PASCAL-JEAN;MILNER, PETER;SALLUSTIO, BENEDETTA;LICARI, JOHN |