DISPOSABLE BIOREACTOR WITH FILTRATION SYSTEM

摘要

A disposable bioreactor system includes a bag having a first end and a second end. An acoustophoresis device is disposed at the first end of the bag, and is separable from the bag. An actuating mechanism is operably connected to the second end of the bag. The actuating mechanism is configured to move the second end of the bag towards the acoustophoresis device, so that fluids within the volume of the bag flow past the acoustophoresis device and carry desired biomolecules out of the bag for collection, while cells and other debris remain within the bag for disposal.

主权项

1. A disposable bioreactor system, comprising:
a bag having a first end, a second end, and a port at the first end; at least one acoustophoresis device disposed about the first end of the bag, the at least one acoustophoresis device being separable from the bag; and an actuating mechanism operably connected to the second end of the bag, the actuating mechanism being configured to move the second end of the bag towards the at least one acoustophoresis device at the first end of the bag.