发明名称 |
Gene-expression profiling with reduced numbers of transcript measurements |
摘要 |
<p>The present invention provides compositions and methods for making and using a transcriptome-wide gene-expression profiling platform that measures the expression levels of only a select subset of the total number of transcripts. Because gene expression is believed to be highly correlated, direct measurement of a small number (for example, 1,000) of appropriately- selected transcripts allows the expression levels of the remainder to be inferred. The present invention, therefore, has the potential to reduce the cost and increase the throughput of full- transcriptome gene-expression profiling relative to the well-known conventional approaches that require all transcripts to be measured.</p> |
申请公布号 |
AU2011237688(B2) |
申请公布日期 |
2015.09.10 |
申请号 |
AU20110237688 |
申请日期 |
2011.04.06 |
申请人 |
THE BROAD INSTITUTE, INC.;DANA-FABER CANCER INSTITUTE, INC.;MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
发明人 |
LAMB, JUSTIN;GOLUB, TODD R.;SUBRAMANIAN, ARAVIND;PECK, DAVID D. |
分类号 |
C40B30/00;C40B30/04;C40B40/06;C40B40/08;G01N31/00;G01N33/48;G01N33/50 |
主分类号 |
C40B30/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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