发明名称 |
HEAT-SENSITIVE AMPHIPHILIC POLYURETHANE AND AQUEOUS SOLUTION CAPABLE OF BEING INJECTED BASED ON SUCH MATERIAL |
摘要 |
A heat-sensitive sol-gel composition capable of being injected is described, composed of an aqueous solution of at least one amphiphilic polyurethane. |
申请公布号 |
US2015250889(A1) |
申请公布日期 |
2015.09.10 |
申请号 |
US201314417736 |
申请日期 |
2013.07.11 |
申请人 |
GELTIS S.r.l. |
发明人 |
Ciardelli Gianluca;Sartori Susanna;Boffito Monica;Serafini Piero |
分类号 |
A61K47/34;A61K9/00;A61L27/26;A61L27/18;A61L27/52 |
主分类号 |
A61K47/34 |
代理机构 |
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代理人 |
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主权项 |
1. Heat-sensitive sol-gel composition capable of being injected composed of an aqueous solution of at least one amphiphilic polyurethane, wherein said amphiphilic polyurethane is adapted to be synthesized through a polymerisation reaction mixture comprising at least:
a first amount (Q1) of at least one and maximum two macrodiols containing at least one block composed of polyethylene glycol (PEG) in a form of an oligomer or a polymer; a second amount (Q2) of at least one diisocyanate with formula OCN—R—NCO, where R is an aliphatic group containing 4 to 26 carbon atoms. |
地址 |
Torino IT |