Preparation of composition comprising gas microbubbles

摘要

A process for preparing a composition comprising encapsulated gas microbubbles, the process comprising: providing an aqueous protein solution of a heat-denaturable protein at a temperature necessary to achieve incipient denaturation; heating a gas by using heat from the heated protein solution; mixing the heated gas and the heated protein solution to obtain a gas/liquid mixture; and dispersing the gas into the protein solution by subjecting the gas/liquid mixture to mechanical shear forces to form a composition of gas microbubbles encapsulated by denatured protein.

主权项

1. A process for preparing a composition comprising encapsulated gas microbubbles, the process comprising:
i) providing an aqueous protein solution of a heat-denaturable protein at a temperature necessary to achieve incipient denaturation; ii) heating a gas by using heat from the heated protein solution; iii) mixing the heated gas and the heated protein solution to obtain a gas/liquid mixture; and iv) dispersing the gas into the protein solution by subjecting the gas/liquid mixture to mechanical shear forces to form a composition of gas microbubbles encapsulated by denatured protein.