发明名称 |
2-acylaminothiazole derivative and salt thereof |
摘要 |
The present inventors achieved the present invention on the basis of the knowledge that a thiazole derivative with a pyrazine-2-carbonylamine substituent at the second carbon position is an excellent positive allosteric modulator of the muscarinic M3 receptor and is useful as a prophylactic and/or therapeutic agent against bladder/urinary tract disorders associated with bladder contractions induced by the muscarinic M3 receptor. A 2-acylaminothiazole derivative or a salt thereof according to the present invention can be used as a prophylactic and/or therapeutic agent against bladder/urinary tract disorders associated with bladder contractions induced by the muscarinic M3 receptor, including, for example, urinary disorders such as underactive bladder. (In the formula, R |
申请公布号 |
AU2014221726(A1) |
申请公布日期 |
2015.09.10 |
申请号 |
AU20140221726 |
申请日期 |
2014.02.27 |
申请人 |
ASTELLAS PHARMA INC. |
发明人 |
TAKAHASHI, TAISUKE;MAEDA, JUN;INAGAKI, YUSUKE;NEGORO, KENJI;TANAKA, HIROAKI;YOKOYAMA, KAZUHIRO;TAKAMATSU, HAJIME;KOIKE, TAKANORI;TSUKAMOTO, ISSEI |
分类号 |
C07D417/14;A61K31/497;A61K31/5377;A61P13/10;A61P43/00;C07D491/107 |
主分类号 |
C07D417/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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