发明名称 |
Anti-IL-12 antibodies, epitopes, compositions, methods and uses |
摘要 |
<p>An anti-IL-12 antibody that binds to a portion of the IL-12 protein corresponding to at least one amino acid residue selected from the group consisting of residues 15, 17-21, 23, 40 43, 45-47, 54-56 and 58-62 of the amino acid sequence of the p40 subunit of IL-12, including isolated nucleic acids that encode at least one anti-IL- 12 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.</p> |
申请公布号 |
AU2015215976(A1) |
申请公布日期 |
2015.09.10 |
申请号 |
AU20150215976 |
申请日期 |
2015.08.24 |
申请人 |
CENTOCOR, INC. |
发明人 |
HEAVNER, GEORGE;GILES-KOMAR, JILL;KNIGHT, DAVID;LUO, JINQUAN;PERITT, DAVID;SCALLON, BERNARD;SHEALY, DAVID |
分类号 |
C12N5/10;A61K39/395;C07K16/24;C12N15/12;C12N15/13;C12N15/62;C12N15/63 |
主分类号 |
C12N5/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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