| 摘要 |
Methods are provided for isolating CD8+ T cells. Furthermore, methods for purifying a subset of IL-13 expressing CD8 T cells are provided, such methods comprising the steps of marking the CD8+ T cells by labeling CD8, or selectively removing non-CD8 cells, and then purifying a subset of IL-13 expressing CD8+ T cells by marking a human biomarker such as C10orf128. Related antibodies and antiserums are also described, such antibodies related to a cell surface domain peptide for biomarker C10orf128, and human homologs of related mouse “activated” CD8IL-13 cell surface biomarkers Tm4sf19 and 1830127L07Rik. |
| 主权项 |
1. A method of purifying a subset of CD8 T cells that make interleukin-13 upon activation, the method comprising:
marking the CD8+ T cells by labeling CD8 or selectively removing all cell types other than CD8+ T cells to isolate the CD8+ T cells, and purifying a subset of CD8+ T cells that make interleukin-13 upon activation by marking one biomarker selected from a group consisting of 1810011H11Rik, Amelx, Dclk3, Mtmr7, Arnt1, Sulf2, Pr2c5, Hpgds, CCR8, and C10orf128. |
