Compositions and methods are provided for making rat pluripotent and totipotent cells, including rat embryonic stem (ES) cells. Compositions and methods for improving efficiency or frequency of germline transmission of genetic modifications in rats are provided. Such methods and compositions comprise an
申请公布号
AU2014218931(A1)
申请公布日期
2015.09.10
申请号
AU20140218931
申请日期
2014.02.20
申请人
REGENERON PHARMACEUTICALS, INC.
发明人
LEE, JEFFREY D.;AUERBACH, WOJTEK;HESLIN, DAVID;FRENDEWEY, DAVID;LAI, KA-MAN VENUS;VALENZUELA, DAVID M.
