发明名称 PLK INHIBITOR SALTS
摘要 <p>The present invention relates to novel crystalline, water-soluble salts of a plk inhibitor. Such crystal salts are for example L-tartrate, succinate, phosphate, mesylate, maleate, L-malate, hydrochloride, fumarate (half mole of counterion), fumarate, citrate (half mole of counterion), benzenesulfonate and L-aspartate (half mole of counterion). New crystal forms of the base as well as solvates and hydrates of such new salt forms, a process for their preparation, their utility in therapy and to the pharmaceutical compositions containing them are also claimed and described in the present application.</p>
申请公布号 EP2459196(B1) 申请公布日期 2015.09.09
申请号 EP20100737027 申请日期 2010.07.22
申请人 NERVIANO MEDICAL SCIENCES S.R.L. 发明人 ZAMPIERI, MASSIMO;BERIA, ITALO;AIROLDI, ANNALISA;CANDIANI, ILARIA;FRIGERIO, RICCARDO
分类号 A61K31/517;A61P25/00;A61P31/12;A61P35/00;A61P37/00;C07D487/14 主分类号 A61K31/517
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