| 摘要 |
<p>Vitamin A is obtained by combining a compound of the formula <FORM:0663733/IV (b)/1> or <FORM:0663733/IV (b)/2> with a compound of the formula <FORM:0663733/IV (b)/3> in which R stands for an alkyl radical by condensing a compound of one of the said formul with an alkali metal acetylide, forming a Grignard derivative of the resulting acetylene compound, and reacting said Grignard derivative with a compound of the other of said formul , reducing the acetylenic linkage of the resulting compound to an ethylene linkage, removing water from at least one of the compounds obtained in the aforesaid operations at a stage subsequent to the introduction of the acetylenic linkage, and replacing the dialkylamino radical of the resulting compound by a hydroxyl radical. Details of the production of 1-[21,61,61-trimethyl cyclohexene-11-yl] - 3 : 7 - dimethyl - 9 - dimethylamino ennea-1 : 3 : 5 : 7-tetraene and its conversion into Vitamin A are given.</p> |
