发明名称 |
MONOSEBACATE OF PYRAZOLE DERIVATIVE |
摘要 |
<p>The present invention provides a novel form of 3-(3-{4-[3-(²-D-gluco-pyranosyloxy)-5-isopropyl-1H-pyrazol-4-ylmethyl]-3-methylphenoxy}propylamino)-2,2-dimethylpropionamide with improved storage stability. Since bis[3-(3-{4-[3-( - D-glucopyranosyloxy)-5-isopropyl-1H-pyrazol-4-ylmethyl]-3-methylphenoxy}pr opylamino)-2,2-dimethylpropionamide] monosebacate has extremely excellent storage stability, it is useful as a drug substance. Furthermore, it shows an extremely good crystalline property and can be purified by a convenient method, and therefore is suitable for the industrial preparation.</p> |
申请公布号 |
EP2228378(B1) |
申请公布日期 |
2015.09.09 |
申请号 |
EP20080867231 |
申请日期 |
2008.12.24 |
申请人 |
KISSEI PHARMACEUTICAL CO., LTD. |
发明人 |
TAKEUCHI, HIDEKI;TSURU, EIJI |
分类号 |
C07H17/02;A61K31/7056;A61P3/00;A61P3/04;A61P3/06;A61P3/08;A61P3/10;A61P7/10;A61P9/04;A61P9/10;A61P9/12;A61P19/06;A61P43/00 |
主分类号 |
C07H17/02 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|