| 摘要 |
This invention relates to a non-invasive method for obtaining samples of olfactory epithelium (OE) cells, such as olfactory sensory neurons (OSNs), from patients. The method comprises directing a jet of sampling solution into a nostril of an individual, recovering the sampling solution from a nostril of the individual, and isolating olfactory epithelium cells from the recovered sampling solution. Samples obtained by this method may be useful in for a range of research and diagnostic applications, including the diagnosis and prognosis of diseases such as CNS disorders, neurodegenerative disease, psychiatric diseases or cancer. |
