Multicomponent immunogenic composition for the prevention of beta-hemolytic streptococcal (BHS) disease

摘要

A number of β-hemolytic streptococci polynucleotides and polypeptides, particularly Streptococcus pyogenes polypeptides and polynucleotides, are described. Two or more of the polypeptides of the invention can be formulated for use as immunogenic compositions. Also disclosed are methods for immunizing against and reducing infection caused by β-hemolytic streptococci.

主权项

1. An immunogenic composition comprising an effective amount of a first polypeptide encoded by a nucleic acid set forth as SEQ ID NO:1 and an effective amount of a second polypeptide encoded by a nucleic acid set forth as SEQ ID NO:7.