发明名称 |
Bone repair material |
摘要 |
The bone repair material comprises the following components:;A) a first granular component with a diameter larger than 20 μm chosen from the group of: calcium phosphate, calcium pyrophosphate, or calcium sulfate dihydrate;;B) a second component chosen from the group of apatite powder with a particle diameter smaller than 1 μm, (preferably smaller than 100 nm); and;B) a third component comprising water or an aqueous solution, whereby;C) the volume fraction of the second and third component represents at least 35 volume-% of the total bone repair material. |
申请公布号 |
US9125966(B2) |
申请公布日期 |
2015.09.08 |
申请号 |
US200512093544 |
申请日期 |
2005.11.15 |
申请人 |
DR. H.C. ROBERT MATHYS STIFTUNG;DEPUY SYNTHES PRODUCTS, INC. |
发明人 |
Bohner Marc;Montali Andrea;Bruderer Yvonne |
分类号 |
A61K8/02;A61K9/00;A61L24/00;A61L24/02;A61L27/12;A61L27/42 |
主分类号 |
A61K8/02 |
代理机构 |
Rankin, Hill & Clark LLP |
代理人 |
Rankin, Hill & Clark LLP |
主权项 |
1. A bone repair material comprising a mixture of:
A) a first granular component having a diameter larger than 20 μm selected from the group consisting of: calcium phosphate, calcium pyrophosphate and calcium sulfate dihydrate; B) a second component consisting of apatite powder having a particle diameter smaller than 1 μm; and C) a third component comprising water or an aqueous solution; wherein the second component and the third component collectively represent at least 35 volume-% of the total bone repair material, wherein the bone repair material forms a paste when the first, second and third components are mixed together to form the mixture, wherein the bone repair material does not contain a hydrogel, and wherein the first granular component provides a scaffold on which bone cells can anchor and proliferate when the bone repair material is used to repair a defect in a bone filled with an aqueous body fluid. |
地址 |
Bettlach CH |