发明名称 Bone repair material
摘要 The bone repair material comprises the following components:;A) a first granular component with a diameter larger than 20 μm chosen from the group of: calcium phosphate, calcium pyrophosphate, or calcium sulfate dihydrate;;B) a second component chosen from the group of apatite powder with a particle diameter smaller than 1 μm, (preferably smaller than 100 nm); and;B) a third component comprising water or an aqueous solution, whereby;C) the volume fraction of the second and third component represents at least 35 volume-% of the total bone repair material.
申请公布号 US9125966(B2) 申请公布日期 2015.09.08
申请号 US200512093544 申请日期 2005.11.15
申请人 DR. H.C. ROBERT MATHYS STIFTUNG;DEPUY SYNTHES PRODUCTS, INC. 发明人 Bohner Marc;Montali Andrea;Bruderer Yvonne
分类号 A61K8/02;A61K9/00;A61L24/00;A61L24/02;A61L27/12;A61L27/42 主分类号 A61K8/02
代理机构 Rankin, Hill & Clark LLP 代理人 Rankin, Hill & Clark LLP
主权项 1. A bone repair material comprising a mixture of: A) a first granular component having a diameter larger than 20 μm selected from the group consisting of: calcium phosphate, calcium pyrophosphate and calcium sulfate dihydrate; B) a second component consisting of apatite powder having a particle diameter smaller than 1 μm; and C) a third component comprising water or an aqueous solution; wherein the second component and the third component collectively represent at least 35 volume-% of the total bone repair material, wherein the bone repair material forms a paste when the first, second and third components are mixed together to form the mixture, wherein the bone repair material does not contain a hydrogel, and wherein the first granular component provides a scaffold on which bone cells can anchor and proliferate when the bone repair material is used to repair a defect in a bone filled with an aqueous body fluid.
地址 Bettlach CH