Nanostructure-initiator mass spectrometry biometrics

摘要

Several embodiments described herein are drawn to methods of identifying an analyte on a subject's skin, methods of generating a fingerprint, methods of determining a physiological change in a subject, methods of diagnosing health status of a subject, and assay systems for detecting an analyte and generating a fingerprint, by nanostructure-initiator mass spectrometry (NIMS).

主权项

1. A method of identifying a subject comprising:
generating a mass spectrum from a nanostructure-initiator mass spectrometry (NIMS) chip, wherein the chip comprises an analyte from the subject's skin; identifying a mass spectrum pattern unique to the subject; comparing the mass spectrum pattern to a known pattern, thereby identifying the subject; wherein generating the mass spectrum comprises contacting the subject's skin to the NIMS chip for applying an analyte on the subject's skin to the NIMS chip, wherein the mass spectrum comprises ions derived from the analyte; and identifying the mass spectrum pattern unique to the subject comprises detecting a pattern of the ions derived from the analyte.