| 发明名称 | Detection of cancer with electrical impedance tomography | ||
| 摘要 | The use of nanoparticles for imaging a tumor in a mammal using electrical impedance tomography. The nanoparticles comprise a core of metal and/or semiconductor atoms to which are linked ligands that comprise a molecule capable of attaching to a specific tumor biomarker. | ||
| 申请公布号 | US9125583(B2) | 申请公布日期 | 2015.09.08 |
| 申请号 | US200913127423 | 申请日期 | 2009.11.06 |
| 申请人 | Middlesex University Higher Education Corporation;Midatech Limited | 发明人 | Bayford Richard Harold;Roitt Ivan Maurice;Rademacher Thomas William;Demosthenous Andreas;Iles Raymond Kruse |
| 分类号 | G01N33/574;A61B5/053;A61K49/00 | 主分类号 | G01N33/574 |
| 代理机构 | Schwegman Lundberg & Woessner, P.A. | 代理人 | Schwegman Lundberg & Woessner, P.A. |
| 主权项 | 1. A method of obtaining an image of a tumour located in a body of a mammal, said method comprising targeting nanoparticles to the tumour, said nanoparticles having a metal core of mean diameter of from 0.5 nm to 10 nm and of core material consisting of gold or a combination of gold and ferrous iron, and a ligand linked to the core and capable of attaching to a tumour biomarker and imaging the tumour by detecting location of the nanoparticles attached to the tumour using electrical impedance tomography (EIT). | ||
| 地址 | GB | ||