发明名称 |
Epoxyeicosatrienoic acid analogs and methods of making and using the same |
摘要 |
Compounds and compositions comprising epoxyeicosatrienoic acid (EET) analogs that act as EET agonists and are useful as medications in the treatment of drug-induced nephrotoxicity, hypertension and other related conditions. Methods of making and using the compounds and compositions are further described. |
申请公布号 |
US9127027(B2) |
申请公布日期 |
2015.09.08 |
申请号 |
US201214009658 |
申请日期 |
2012.04.04 |
申请人 |
The Medical College of Wisconsin, Inc.;The Board of Regents of the University of Texas System |
发明人 |
Imig John David;Campbell William B.;Falck John Russell |
分类号 |
A61K31/66;C07F9/40;C07C233/46;C07C233/56;C07C275/20;C07C309/15;C07C311/18;C07C311/51;C07C317/28;C07C323/44;C07D249/12;C07D257/04;C07D271/06;C07D277/34;C07D277/82;C07D291/04;C07C233/47;C07C237/22;C07C311/19;C07D271/07;C07D277/593;C07D285/08 |
主分类号 |
A61K31/66 |
代理机构 |
Quarles & Brady LLP |
代理人 |
Quarles & Brady LLP |
主权项 |
1. A compound selected from the group consisting of |
地址 |
Milwaukee WI US |