Human protein tyrosine phosphatase inhibitors and methods of use

摘要

The present disclosure relates to compounds effective as human protein tyrosine phosphatase beta (HPTP-β) inhibitors thereby regulating angiogenesis. The present disclosure further relates to compositions comprising said human protein tyrosine phosphatase beta (HPTP-β) inhibitors, and to methods for regulating angiogenesis.

主权项

1. A compound of the formula: R is a thiazolyl group that is substituted or unsubstituted; R1 is alkyl, phenyl, or benzyl, any of which is substituted or unsubstituted, or hydrogen; R2 is alkyl or alkoxy; and R3 is hydrogen or alkyl,or a pharmaceutically-acceptable salt thereof.