| 发明名称 | Crystalline rostafuroxin | ||
| 摘要 | New crystalline forms of 17β-(3-Furyl)-5-βandrostane-3β,14β,17α-triol are described together with pharmaceutical composition containing the same and methods for their preparation. In particular new Forms B, C, D, E and H are here described. | ||
| 申请公布号 | US9127037(B2) | 申请公布日期 | 2015.09.08 |
| 申请号 | US200612094885 | 申请日期 | 2006.11.23 |
| 申请人 | ROSTAQUO S.P.A. | 发明人 | Cerri Alberto;Armaroli Silvia;Torri Marco |
| 分类号 | C07J17/00 | 主分类号 | C07J17/00 |
| 代理机构 | Lucas & Mercanti, LLP | 代理人 | Lucas & Mercanti, LLP |
| 主权项 | 1. A method for preparing crystalline, rostafuroxin Form F, consisting of dissolving rostafuroxin, amorphous, in ethanol to form a solution and then adding dropwise said solution to an excess of water at room temperature, and thereafter isolating crystalline rostafuroxin Form F having 2.5 moles of water per mole of rostafuroxin. | ||
| 地址 | Pomezia (RM) IT | ||