| 发明名称 |
ANTIBODIES FOR EPIDERMAL GROWTH FACTOR RECEPTOR 3 (HER3) DIRECTED TO DOMAIN II OF HER3 |
| 摘要 |
<p>The present invention relates to antibodies or fragments thereof that target an epitope of a HER3 receptor residing in domain 2 of the HER3 receptor to block both ligand dependent and ligand independent signal transduction and tumor growth; and compositions and methods of use thereof.</p> |
| 申请公布号 |
IN4373CHN2014(A) |
申请公布日期 |
2015.09.04 |
| 申请号 |
IN2014CH04373 |
申请日期 |
2014.06.12 |
| 申请人 |
NOVARTIS AG |
发明人 |
ELIS WINFRIED;ETTENBERG SETH;GARNER ANDREW PAUL;KUNZ CHRISTIAN CARSTEN SILVESTER;SEITZ TOBIAS |
| 分类号 |
C07K16/32;A61K39/395;A61P35/00 |
主分类号 |
C07K16/32 |
| 代理机构 |
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